Tag: itraconazole

Proton Pump Inhibitors and Antifungals: How They Interfere With Absorption and Effectiveness

Proton pump inhibitors can severely reduce absorption of some antifungals like itraconazole and ketoconazole, leading to treatment failure. Fluconazole and echinocandins are safer alternatives. New research also suggests PPIs may boost antifungal power against resistant fungi.