Weight-Loss Medication Eligibility Checker
Find the right medication for you
Answer a few questions to see which weight-loss medications may be suitable for your situation.
Trying to lose those stubborn kilos can feel like navigating a maze. One shortcut many people hear about is Trim Z, a prescription‑only version of the fat‑blocker Orlistat. But is it really the best stop on the road to a healthier weight, or do other pills suit you better? Below we break down how Trim Z works, what to look for in a weight‑loss drug, and how it stacks up against the most common alternatives.
What is Trim Z (Orlistat) and how does it work?
Trim Z is a prescription formulation of the lipase inhibitor Orlistat, designed to block the absorption of about one‑third of dietary fat. When you take a dose with a meal that contains fat, the drug binds to pancreatic lipases in the gut and prevents them from breaking down fat molecules. The undigested fat is then eliminated in the stool.
The effect is purely mechanical - it doesn’t touch appetite hormones or metabolism. Because of that, Trim Z works best when paired with a low‑fat, calorie‑controlled diet and regular exercise. Clinical trials in the UK and NZ reported an average weight loss of 5‑10% of initial body weight over 12 weeks when used correctly.
Key criteria for comparing weight‑loss medications
Before diving into the side‑by‑side numbers, it helps to know which factors matter most to most people:
- Mechanism of action: Does the drug cut calories, curb appetite, or block fat absorption?
- Prescription status: Is a doctor’s script needed, or can you buy it over the counter?
- Typical weight‑loss results: What percentage of body weight can you expect to lose in three months?
- Side‑effect profile: Are the side effects mild (dry mouth) or potentially serious (elevated heart rate)?
- Cost in New Zealand: How much does a month’s supply run?
- Eligibility requirements: Minimum BMI, presence of comorbidities, or contraindications.
Keeping these points in mind makes the upcoming comparison easier to read.
Head‑to‑head comparison
| Medication | Mechanism | Prescription? | Avg. % weight loss (12 weeks) | Main side effects | Typical NZ monthly cost |
|---|---|---|---|---|---|
| Trim Z (Orlistat) | Fat‑absorption inhibitor | Prescription | 5‑10 % | Oily stools, flatulence, abdominal cramps | ~$120 |
| Phentermine | Appetite suppressant (sympathomimetic) | Prescription | 7‑12 % | Insomnia, dry mouth, increased heart rate | ~$65 |
| Contrave | Combination of bupropion & naltrexone (appetite & reward) | Prescription | 5‑9 % | Nausea, constipation, dizziness | ~$140 |
| Saxenda (liraglutide) | GLP‑1 agonist (hormone‑like) | Prescription | 8‑12 % | nausea, vomiting, pancreatitis risk | ~$340 |
| Wegovy (semaglutide) | GLP‑1 agonist (strong appetite control) | Prescription | 12‑15 % | Nausea, diarrhea, gallbladder issues | ~$420 |
| Qsymia (phentermine/topiramate) | Appetite suppressant + anti‑seizure (synergistic) | Prescription | 8‑12 % | Tingling, mood changes, birth defects risk | ~$115 |
| Alli (OTC Orlistat) | Fat‑absorption inhibitor (lower dose) | Over‑the‑counter | 3‑5 % | Oily stools, fecal urgency | ~$70 |
The table shows that Trim Z is among the cheapest prescription options, but its weight‑loss ceiling sits below the GLP‑1 drugs (Saxenda, Wegovy). If you’re comfortable with an injectable and can afford the higher price, the GLP‑1 class often delivers double‑digit percentage loss.
Pros and cons of Trim Z
Pros
- Non‑systemic: works only in the gut, so it doesn’t affect heart rate or blood pressure.
- Well‑studied: over two decades of clinical data, including the landmark NZ Ministry of Health endorsement for BMI ≥ 30.
- Cost‑effective compared with newer injectables.
Cons
- Gastrointestinal side effects can be socially embarrassing.
- Requires strict low‑fat diet; otherwise, side effects intensify.
- Weight‑loss ceiling typically caps at ~10 % of body weight.
Quick looks at the alternatives
Phentermine is a stimulant that curbs appetite by releasing norepinephrine. It’s fast‑acting but unsuitable for people with heart disease.
Contrave combines bupropion and naltrexone to target reward pathways in the brain. It works well for those who struggle with cravings, yet it can raise blood pressure.
Saxenda (liraglutide) is a daily injectable that mimics GLP‑1, slowing stomach emptying and reducing appetite. The injection routine and higher price are its main hurdles.
Wegovy (semaglutide) is the newest GLP‑1, given weekly, and boasts the strongest weight‑loss numbers. Insurance coverage is improving, but cost remains a barrier.
Qsymia pairs phentermine with topiramate. It offers solid results but carries a warning for pregnancy‑related birth defects.
Alli is the over‑the‑counter, lower‑dose sibling of Trim Z. It’s the most accessible option, yet its weight‑loss impact is modest.
How to choose the right medication for you
Answer these three quick questions before you book a consultation:
- Do you have any heart, blood‑pressure, or psychiatric conditions? If yes, stimulants like Phentermine or Qsymia may be off‑limits.
- Can you commit to a low‑fat diet? Trim Z and Alli work only when you keep dietary fat under 30 g per meal.
- What’s your budget? GLP‑1 injectables can exceed $400 NZ per month, while Trim Z sits around $120.
If your answers line up with a low‑fat diet, no cardiovascular concerns, and a moderate budget, Trim Z is a sensible first‑line choice. If you need stronger appetite control or have struggled with bariatric‑type hunger, a GLP‑1 (Saxenda/Wegovy) may be worth the extra cost.
Frequently Asked Questions
Can I buy Trim Z without a prescription in New Zealand?
No. Trim Z is a prescription‑only medication. You’ll need a doctor’s approval, usually after confirming a BMI ≥ 30 or a BMI ≥ 27 with weight‑related health issues.
How soon will I see results with Trim Z?
Most people notice modest weight loss within the first 4-6 weeks if they stick to a low‑fat diet and take the pill with each main meal.
Are the gastrointestinal side effects dangerous?
They’re not dangerous but can be uncomfortable. Taking a multivitamin with fat‑soluble vitamins and limiting dietary fat greatly reduces the odds of oily stools.
Is Trim Z suitable for people with diabetes?
Yes, as long as blood‑sugar monitoring is continued. Orlistat does not affect glucose metabolism, but the reduced fat intake can improve insulin sensitivity.
How does Trim Z compare to the over‑the‑counter Alli?
Both contain Orlistat, but Trim Z uses a higher 120 mg dose per capsule versus Alli’s 60 mg. This translates to greater fat‑blocking capacity and slightly better weight‑loss outcomes, at the expense of a prescription requirement.
Whatever path you choose, pairing medication with a realistic diet plan and regular activity gives the best chance of lasting results. Talk to a qualified healthcare professional to see if Trim Z or one of its alternatives fits your health profile.
